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Results for "

Low-density lipoprotein receptor

" in MedChemExpress (MCE) Product Catalog:

19

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1

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1

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2

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2

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15

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2

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5

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Cat. No. Compare Product Name Species Source
  • HY-P70235
    LDLR Protein, Human (HEK293, His)
    1 Publications Verification

    rHuLow-density lipoprotein receptor/LDLR, His; Low-density lipoprotein receptor; LDL receptor; LDLR

    		 Human HEK293
    LDLR Protein plays a pivotal role in cholesterol homeostasis, binding to LDL and mediating cellular uptake through endocytosis. Clustering into clathrin-coated pits is essential for internalization. In microbial infection, LDLR acts as a receptor for hepatitis C virus in hepatocytes, emphasizing its dual functionality in cholesterol metabolism and the cellular response to viral infections. LDLR Protein, Human (HEK293, His) is the recombinant human-derived LDLR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LDLR Protein, Human (HEK293, His) is 767 a.a., with molecular weight of 99-135 kDa.
  • HY-P73272
    LDLR Protein, Mouse (HEK293, His)

    Low-density lipoprotein receptor; LDLR; LDL receptor

    		 Mouse HEK293
    LDLR Protein crucially binds to LDL, transporting cholesterol through endocytosis. Clustering into clathrin-coated pits initiates internalization. Interactions with DAB2, LDLRAP1, ARRB1, SNX17, and immature PCSK9 contribute to its functional versatility. The NPXY motif interaction is impaired by tyrosine phosphorylation. LDLR Protein, Mouse (HEK293, His) is the recombinant mouse-derived LDLR protein, expressed by HEK293 , with C-His labeled tag. The total length of LDLR Protein, Mouse (HEK293, His) is 769 a.a., with molecular weight of ~98-130 kDa.
  • HY-P73838
    LDLR Protein, Mouse (Biotinylated, A23V, C27G, HEK293, His)

    Low-density lipoprotein receptor; LDLR; LDL receptor

    		 Mouse HEK293
    LDLR Protein crucially binds to LDL, transporting cholesterol through endocytosis. Clustering into clathrin-coated pits initiates internalization. Interactions with DAB2, LDLRAP1, ARRB1, SNX17, and immature PCSK9 contribute to its functional versatility. The NPXY motif interaction is impaired by tyrosine phosphorylation. LDLR Protein, Mouse (Biotinylated, A23V, C27G, HEK293, His) is the recombinant mouse-derived LDLR protein, expressed by HEK293 , with C-His labeled tag and A23V, C27G mutation. The total length of LDLR Protein, Mouse (Biotinylated, A23V, C27G, HEK293, His) is 790 a.a., with molecular weight of ~85.7 kDa.
  • HY-P72392
    LDLR Protein, Human (Biotinylated, HEK293, Avi-His)

    Low-density lipoprotein receptor; LDL receptor; LDLR

    		 Human HEK293
    LDLR Protein plays a pivotal role in cholesterol homeostasis, binding to LDL and mediating cellular uptake through endocytosis. Clustering into clathrin-coated pits is essential for internalization. In microbial infection, LDLR acts as a receptor for hepatitis C virus in hepatocytes, emphasizing its dual functionality in cholesterol metabolism and the cellular response to viral infections. LDLR Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived LDLR protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of LDLR Protein, Human (Biotinylated, HEK293, Avi-His) is 767 a.a., with molecular weight of 95-140 kDa.
  • HY-P76477
    LRP-11 Protein, Human (HEK293, His)

    Low-density lipoprotein receptor-related protein 11; LRP-11

    		 Human HEK293
  • HY-P77057
    LDLRAD3 Protein, Human (HEK293, Fc)

    Low-density lipoprotein receptor class A domain-containing protein 3; LRAD3

    		 Human HEK293
    LDLRAD3 protein significantly affects the processing of amyloid precursor protein (APP), possibly reducing soluble APP-α (sAPP-α) and increasing the production of amyloid P3 peptide. Suggested regulation of ITCH and NEDD4 E3 ligases. LDLRAD3 Protein, Human (HEK293, Fc) is the recombinant human-derived LDLRAD3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of LDLRAD3 Protein, Human (HEK293, Fc) is 156 a.a., with molecular weight of ~43.8 KDa.
  • HY-P77057A
    LDLRAD3 Protein, Human (HEK293, hFc)

    Low-density lipoprotein receptor class A domain-containing protein 3; LRAD3

    		 Human HEK293
  • HY-P76475
    LRP-10 Protein, Human (HEK293, Fc)

    Low-density lipoprotein receptor-related protein 10; LRP-10; MSTP087; SP220

    		 Human HEK293
    The LRP-10 protein is a possible receptor that may mediate internalization and/or signaling of lipophilic molecules. It is speculated that LRP-10 can promote the uptake of lipoprotein APOE in the liver and may play a role in lipid metabolism and processes related to lipoprotein transport. LRP-10 Protein, Human (HEK293, Fc) is the recombinant human-derived LRP-10 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of LRP-10 Protein, Human (HEK293, Fc) is 440 a.a., with molecular weight of 80-90 KDa.
  • HY-P76476
    LRP-10 Protein, Human (HEK293, His)

    Low-density lipoprotein receptor-related protein 10; LRP-10; MSTP087; SP220

    		 Human HEK293
    The LRP-10 protein is a possible receptor that may mediate internalization and/or signaling of lipophilic molecules. It is speculated that LRP-10 can promote the uptake of lipoprotein APOE in the liver and may play a role in lipid metabolism and processes related to lipoprotein transport. LRP-10 Protein, Human (HEK293, His) is the recombinant human-derived LRP-10 protein, expressed by HEK293 , with C-His labeled tag. The total length of LRP-10 Protein, Human (HEK293, His) is 424 a.a., with molecular weight of ~55 KDa.
  • HY-P70946
    LRP-12 Protein, Human (HEK293, His)

    Low-density lipoprotein receptor-Related Protein 12; LRP-12; Suppressor of Tumorigenicity 7 Protein; LRP12; ST7

    		 Human HEK293
    LRP-12, a probable receptor, potentially facilitates the internalization of lipophilic molecules and signal transduction. It may function as a tumor suppressor and interacts with proteins RACK1, ZFYVE9, and NMRK2. LRP-12 Protein, Human (HEK293, His) is the recombinant human-derived LRP-12 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LRP-12 Protein, Human (HEK293, His) is 456 a.a., with molecular weight of ~64-85 kDa.
  • HY-P76125
    VLDLR Protein, Human (HEK293, His)

    Very Low-density lipoprotein receptor; VLDL-R

    		 Human HEK293
    VLDLR protein, a versatile receptor, mediates energy metabolism by binding and transporting VLDL into cells. It interacts with Reelin/RELN, APOE-containing ligands, and clusterin/CLU. Inactive VLDLR forms oligomers with LRP8, but upon ligand binding, it rearranges to transmit the extracellular RELN signal via DAB1 phosphorylation, regulating neuron positioning. VLDLR also acts as a stop signal for migrating neurons and serves as a receptor for Semliki Forest virus during microbial infection. VLDLR Protein, Human (HEK293, His) is the recombinant human-derived VLDLR protein, expressed by HEK293, with C-His labeled tag. The total length of VLDLR Protein, Human (HEK293, His) is 770 a.a., with molecular weight (glycosylation form) of 110-130 kDa.
  • HY-P73835
    LOX-1/OLR1 Protein, Rat (HEK293, His)

    Oxidized Low-density lipoprotein receptor 1; LOX-1; OLR1; CLEC8A

    		 Rat HEK293
    The LOX-1/OLR1 protein plays an important role as a receptor that recognizes, internalizes, and degrades oxidatively modified low-density lipoprotein (oxLDL), a marker of atherosclerosis, in vascular endothelial cells. OxLDL induces endothelial dysfunction, triggering pro-inflammatory responses, oxidative conditions, and apoptosis. LOX-1/OLR1 Protein, Rat (HEK293, His) is the recombinant rat-derived LOX-1/OLR1 protein, expressed by HEK293 , with N-His labeled tag. The total length of LOX-1/OLR1 Protein, Rat (HEK293, His) is 305 a.a., with molecular weight of 43-47 kDa.
  • HY-P73836
    LOX-1/OLR1 Protein, Rat (HEK293, Fc)

    Oxidized Low-density lipoprotein receptor 1; LOX-1; OLR1; CLEC8A

    		 Rat HEK293
    The LOX-1/OLR1 protein plays an important role as a receptor that recognizes, internalizes, and degrades oxidatively modified low-density lipoprotein (oxLDL), a marker of atherosclerosis, in vascular endothelial cells. OxLDL induces endothelial dysfunction, triggering pro-inflammatory responses, oxidative conditions, and apoptosis. LOX-1/OLR1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived LOX-1/OLR1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of LOX-1/OLR1 Protein, Rat (HEK293, Fc) is 305 a.a., with molecular weight of ~66 & 35 kDa, respectively.
  • HY-P76474
    LOX-1/OLR1 Protein, Cynomolgus (HEK293, His)

    Oxidized Low-density lipoprotein receptor 1; LOX-1; OLR1; CLEC8A

    		 Cynomolgus HEK293
    OLR1 is a type II membrane glycoprotein belonging to C-type lectin family with a short N-terminal cytoplasmic tail and a long C-terminal extracellular domain. OLR1 binds ox-LDL, delipidated, and solubilized ox-LDL. LOX-1/OLR1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived LOX-1/OLR1 protein, expressed by HEK293 , with N-His labeled tag. The total length of LOX-1/OLR1 Protein, Cynomolgus (HEK293, His) is 213 a.a., with molecular weight of ~37 KDa.
  • HY-P71180
    OLR1 Protein, Human (HEK293, His)

    Oxidized Low-density lipoprotein receptor 1; Ox-LDL receptor 1; C-Type Lectin Domain Family 8 Member A; Lectin-Like Oxidized LDL receptor 1; LOX-1; Lectin-Like oxLDL receptor 1; hLOX-1; Lectin-Type Oxidized LDL receptor 1; OLR1; CLEC8A; LOX1

    		Human HEK293
    OLR1 Protein, a receptor on vascular endothelial cells, plays a key role in recognizing, internalizing, and degrading oxidatively modified low-density lipoprotein (oxLDL). As a marker of atherosclerosis, oxLDL induces vascular endothelial cell activation, leading to pro-inflammatory responses, oxidative conditions, and apoptosis. OLR1's association with oxLDL activates NF-kappa-B, contributing to pro-atherogenic responses such as reduced nitric oxide release, monocyte adhesion, and apoptosis. Beyond oxLDL, it serves as a receptor for HSP70, participating in cell-mediated antigen cross-presentation and functioning as a leukocyte-adhesion molecule in inflammation. Additionally, OLR1 recognizes AGE products, activated platelets, monocytes, apoptotic cells, and bacteria. OLR1 Protein, Human (HEK293, His) is the recombinant human-derived OLR1 protein, expressed by HEK293, with C-6*His labeled tag. The total length of OLR1 Protein, Human (HEK293, His) is 213 a.a., with molecular weight of 30-35 kDa.

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